Postdoctoral Associate, Immunology, Weiss Lab
- Massachusetts Institute of Technology
- Location: Cambridge, Massachusetts
- Category: Admin-Laboratory and Research
- Posting Date: 11/27/2021
- Application Deadline: Open until filled
Working at MIT offers opportunities, an environment, a culture – and benefits – that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future – then take a look at this opportunity.
Information on MIT’s COVID-19 vaccination requirement can be found at the bottom of this posting.
POSTDOCTORAL ASSOCIATE, Biological Engineering-Synthetic Biology Center-Weiss Lab , to join an interdisciplinary research lab seeking to create integrated biological systems capable of autonomously performing useful tasks and to elucidate the design principles underlying the engineering of complex cellular and tissue phenotypes. Will pursue research on synthetic antiviral systems to address SARS-Cov2 and other applications of synthetic immunology with a focus on developing in vivo mouse models for validations of therapeutic efficacy. Synthetic immune responses will be guided by mammalian genetic circuits that will sense cell state, including mRNA, miRNA, metabolites, viral entry, etc., and implement functions that result in precise responses such as transcription factors cytokine expression or repression and antiviral therapy. Responsibilities include designing sophisticated genetic circuits (e.g., using CRISPR/Cas9, molecular cloning, mammalian cell culture, DNA transfection, lentiviral transduction); designing assays; collecting data using state-of-the-art techniques, including flow cytometry, RT-qPCR, next-generation sequencing, ELISA, and other technologies; working with cross-functional teams for microfluidic and high-throughput scale-up; data analysis; communicating results to team members; making presentations to the scientific community through talks and publications; and performing other tasks as needed.
REQUIRED: Ph.D. in biological sciences, computer science, engineering, physics, math, or related field; experience in at least one of the following--immunology, mammalian cell culture, large scale DNA assembly and characterization, genetic recombination technology, next-generation sequencing, computational methods and tools for analysis, and statistics; biological experience in molecular biology, protein engineering, immunology, and/or cell biology; ability to prioritize, perform multiple tasks, and execute detailed technical protocols meticulously; strong organizational, analytical, problem-solving, and documentation skills; and ability to work collaboratively and on individual projects in a dynamic, multidisciplinary, team-oriented setting. Job #20458