Scientist, In Vivo Electrophysiology

Job Description

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

What We Do:

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie

About the Role:

Neurocrine Biosciences, Inc. (NASDAQ: NBIX) seeks a Scientist to join the In Vivo Electrophysiology team withing the Translational Sciences group. The successful candidate will perform experiments and analyze data, especially rodent electroencephalography (EEG), related to neural circuit analysis to support drug discovery programs. In addition, this individual will help develop new in vivo electrophysiology/optical assays and perform pharmacologic/animal model characterization studies to support target validation, lead optimization, translation, and understanding mechanisms of drug action.

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Your Contributions (include, but are not limited to):
  • Supporting a range of activities, including in vivo and translational research

  • Design, implementation, and data collection of pharmaco-EEG experiments

  • Analysis & interpretation of qEEG data (spectral analysis, sleep staging)

  • Small animal handling/dosing, drug formulation, and tissue collection

  • Roden survival (i.e., stereotaxic) surgery & behavioral experiments

  • Interacting with other research areas within the company

  • Aid in development of novel in vivo electrophysiology/imaging experimental approaches

  • With proper training, conduct experiments independently on a schedule to meet required timelines

  • Histology and imaging of slides

  • This role is divided between lab-based (vivarium) work, and computer-based (data analysis) work

  • Supporting a range of activities, including in vivo and translational research

Requirements:
  • BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and 2+ years of experience in the handling and dosing of rodents in a laboratory setting OR

  • MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred OR

  • PhD degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some relevant experience preferred

  • Expertise in one or more of the following techniques is required: In vivo electrophysiology (including EEG, LFP, or spikes), in vivo microscopy, microdialysis, fiber photometry, transcranial magnetic stimulation, functional MRI, or functional ultrasound imaging.

  • Prior experience in the pharmaceutical or biotechnology industry desired but is not required

  • Familiarity with biopharmaceutical technologies, physical and life sciences, product development, and regulatory approval processes is desirable

  • Experience in programming (Matlab or Python) strongly preferred

  • Previous experience with stereotaxic surgery, AAV administration and/or mouse colony maintenance and breeding preferred

  • Recognizes fundamental anomalies in data points and identifies issues in experiments/processes

  • Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals

  • Strong knowledge of one scientific discipline

  • Good knowledge of scientific principles, methods and techniques

  • Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools

  • Strong computer skills

  • Good communications, problem-solving, analytical thinking skills

  • Ability to meet deadlines

  • Good project management skills

  • High level of organization and attention to detail

  • Willingness and ability to work both independently and as part of a team

  • Must have working knowledge of Microsoft Office, Word, and Excel

  • Advanced multitasking, trouble shooting and deductive reasoning skills required

#LI-OB1

Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.

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The annual base salary we reasonably expect to pay is $86,200.00-$125,050.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

 

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