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Bioscience Postdoc
Los Alamos National Security in
Date Posted September 21, 2020
Admin-Other Administrative Positions
Employment Type
Application Deadline Open until filled

What You Will Do

The Bioscience Division at Los Alamos National Laboratory is seeking two motivated, enthusiastic Postdoctoral Research Associates to work on a multi-scale genomics project that encompasses epigenetics, virology, genomics, bioinformatics, and advanced visualization. The objective of this project is to re-envision what it means to ‘sequence a genome’. As a part of this effort, we are advancing the science and technology of genome mapping by developing new 4-dimensional genomics capabilities. Our goal is to deploy these capabilities to discover fundamental cellular functions that are hijacked by viruses to cause disease. The postdoc candidates will work closely with a large team of scientists, postdoctoral researchers, and students as part of this multi-disciplinary research project.

Experimental Epigenetics Position:

We are seeking an independent candidate interested in studying epigenetic regulatory mechanisms that control pathogenicity of viral infections in human cells. Using epigenetics assays (including ChIP-seq, ATAC-seq), you will determine how viruses impact the epigenome and contribute to altering the 3D structure of the human genome. This position is ideal for a scientist with a strong background in virology or immunology, who wants to expand her/his expertise into epigenetics and genomics. Candidates with expertise in experimental or computational epigenetics are highly encouraged to apply.

Bioinformatics Position:

In this role, you will be responsible for analyzing a variety of NGS datasets that support the modeling and visualization of 3-dimensional genome architecture including but not limited to data generated from HiC, single cell HiC, ChIPseq, and ATAC-seq assays.

These positions will be filled in either Bioenergy and Biome Sciences or Biosecurity & Public Health group, depending on the skills of the selected candidates.

What You Need

Minimum Job Requirements:

Experimental Epigenetics Position:

  • Background/education in related biological discipline (Biomedical Sciences, Microbiology,Cell & Molecular Biology, Biochemistry, Immunology)

  • Expertise in molecular biology techniques (including protocol development and execution)

  • Experience with mammalian cell culture

  • Experience with pathogen exposure or detection (viruses or bacteria)

  • Excellent communication and writing skills

Bioinformatics Position:

  • Background/education in a related biological discipline (i.e. Microbiology, Cell & Molecular Biology, Biotechnology, Computational Biology)

  • Fluency in one or more coding languages (Python preferred)

  • Experience working within a high performance computing environment

  • Demonstrated experience analyzing and building workflows for NGS and/or epigenetics data

  • Familiarity with library preparation and quality control for targeted next-generation sequencing

Education : Ph.D in Biomedical Sciences, Microbiology, Cell & Molecular Biology, Biochemistry, Immuniology, Biotechnology, or Computational Biology completed within 5 years or will have completed all Ph.D requirements by commencement of appointment.

Desired Qualifications:

Experimental Epigenetics Position:

  • Familiarity with epigenetics data sets, including computational analysis and pipeline development

  • Experience with ATAC-seq, ChIP-seq, RNA-seq, MeDIP-seq, or WGBS

  • Working knowledge of one or more programming languages (e.g. C++, Python, Perl, Java)

  • Experience with NGS and Illumina, PacBio, or Oxford Nanopore sequencing data

  • A strong publication record

Bioinformatics Position:

  • Experience with data and algorithms that support molecular dynamic simulations of DNA/RNA

  • Experience with software and analysis pipelines that enable 2D and 3D visualization of the human genome

Note to Applicants:

These positions are for two years with a third year contingent upon excellent performance. Exceptional candidates may be considered for a Director's Fellowship and outstanding candidates may be considered for the prestigious Dianne Christian Hoffman, Richard P. Feynman, J. Robert Oppenheimer, or Frederick Reines Fellowships. For general information about the Postdoc Program, including salary guidelines, go to:

https://www.lanl.gov/careers/career-options/postdoctoral-research/index.php .

The application package consists of a CV, a cover letter, and a list of three references (who will not be contacted unless an interview is scheduled). A statement of research interests is not required but is highly encouraged. In addition to applying online, candidates may email their CV and cover letter to Christina Steadman ( crt@lanl.gov ) (forexperimental epigenetics) or Shawn Starkenburg ( shawns@lanl.gov ) (for bioinformatics). No candidate is expected to have all of the desired skills. Those who meet the education and minimum job requirements are encouraged to apply.

Additional Details

Position does not require a security clearance. Selected candidates will be subject to drug testing and other pre-employment background checks.

New-Employment Drug Test: The Laboratory requires successful applicants to complete a new-employment drug test and maintains a substance abuse policy that includes random drug testing.

Equal Opportunity: Los Alamos National Laboratory is an equal opportunity employer and supports a diverse and inclusive workforce. All employment practices are based on qualification and merit, without regard to race, color, national origin, ancestry, religion, age, sex, gender identity, sexual orientation or preference, marital status or spousal affiliation, physical or mental disability, medical conditions, pregnancy, status as a protected veteran, genetic information, or citizenship within the limits imposed by federal laws and regulations. The Laboratory is also committed to making our workplace accessible to individuals with disabilities and will provide reasonable accommodations, upon request, for individuals to participate in the application and hiring process. To request such an accommodation, please send an email to applyhelp@lanl.gov or call 1-505-665-4444 option 1.

Where You Will Work

Teams within the Bioscience Division at Los Alamos National Laboratory (LANL) perform research in a broad array of applications of biotechnology and life sciences, working to solve national bioenergy and biosecurity challenges—from naturally occurring or manmade threats—requiring an in-depth understanding of pathogens, plants, and human disease.

Located in beautiful northern New Mexico, Los Alamos National Laboratory (LANL) is a multidisciplinary research institution engaged in strategic science on behalf of national security. Our generous benefits package includes:

  • PPO or High Deductible medical insurance with the same large nationwide network

  • Dental and vision insurance

  • Free basic life and disability insurance

  • Paid maternity and parental leave

  • Award-winning 401(k) (6% matching plus 3.5% annually)

  • Learning opportunities and tuition assistance

  • Flexible schedules and time off (paid sick, vacation, and holidays)

  • Onsite gyms and wellness programs

  • Extensive relocation packages (outside a 50 mile radius)

Appointment Type



Contact Details
Contact Name
Work Telephone
Vacancy Name: IRC81976
Organization Name B-DO/Bioscience
Minimum Salary
Maximum Salary
Req ID: IRC81976
Category: Postdoc

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