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Immunology of HIV and Cancer – Departments of Pathology and Microbiology
University of Alabama at Birmingham in the Birmingham , Alabama
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Date Posted July 17, 2019
Postdoctoral-Health Sciences
Employment Type Full-time
Application Deadline Open until filled
Mentor:  Zdenek Hel, PhD, Associate Professor, Division of Molecular and Cellular Pathology, Department of Pathology, Department of Microbiology, University of Alabama at Birmingham, 1825 University Blvd, Birmingham AL 35294-2182. E-mail: zhel@uab.edu 

A post-doctoral position is available immediately in the fascinating field of immunology of HIV-1 and cancer. The major focus of our laboratory is to understand the role of neutrophils in the regulation of immune responses in chronic infections, cancer, and autoimmune diseases. Neutrophils, the largest circulating immune cell population in the body, have been traditionally recognized as essential innate immune effector cells. However, this view has significantly changed due to the recently accumulated evidence that highlights the role played by neutrophils in the regulation of function of other cell types, in particular T cells, macrophages, and dendritic cells. Neutrophil extracellular traps (NETs), chromatin-based structures extruded from neutrophils upon activation, may mediate the development of cardiovascular disease, vasculitis, and stroke.  We address the role of neutrophils in a plethora of disorders including HIV-1 infection, cancer, lupus, rheumatoid arthritis, combined deficiency, cardiovascular disease, decreased responsiveness to immunization, etc.  

Approaches of studies will involve immunology, molecular biology, protein analyses, high throughput gene expression analyses, microbiome, clinical trials, targeted therapies, and studies in pre-clinical mouse models. Candidates must have a Ph.D., M.D., or equivalent degree. Priority will be given to qualified candidates with a strong background in immunology, cell culture, and molecular biology. The candidate will be expected to write and think independently with passion for innovative research. He/she should be able to analyse data and write manuscripts. Salary (with benefits) will follow NIH guidelines commensurate with training and experience. Competitive applicants should have a proven track record with publications. UAB is a highly collegial and interactive environment that has an active Office of Post-doctoral Education which provides mentoring and career guidance in addition to that provided by the mentor. 

If interested, please send a letter describing your research experience, interests, and future career goals, your CV, and contact information for three references electronically to zhel@uab.edu 

More info about division and laboratory: http://www.uab.edu/medicine/pathology/divisions-sidemenu/molecular-a-cellular

Postdoc Awards and Benefits 

Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The OPE strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.
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