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Postdoctoral position: Membrane biology
University of Alabama at Birmingham in Birmingham, Alabama
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Date Posted July 08, 2020
Employment Type Full-time
Application Deadline Open until filled

Stuart Frank, M.D., Professor and Director, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Alabama at Birmingham, BDB 861, Birmingham AL 35233-0006. E-mail: sjfrank@uab.edu

André Leier, Ph.D., Assistant Professor, Department of Genetics and Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, 1900 University Blvd, THT 136, Birmingham AL 35233-0006. E-mail: aleier@uabmc.edu

Position Description:

A postdoctoral position is available for a highly-motivated individual in the group of Dr. André Leier, Department of Genetics and Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, to study cell membrane-associated processes. The mentoring is shared with Dr. Stuart Frank from the Division of Endocrinology, Diabetes and Metabolism, Department of Medicine. The main project is dedicated to deciphering the collective dynamics and functioning of growth hormone and prolactin receptors (GHR/PRLR) in normal and cancerous cells. Additional studies may focus on interference with other receptor/signaling systems such as EGFR and IGFR as well as mechanobiological aspects of GHR/PRLR signaling. The successful candidate will perform original research using biochemical, molecular and cell biological approaches, in particular super resolution imaging.

Following UAB standards, the appointment will be for one year with the possibility of extension for up to 3 additional years contingent on satisfactory performance and funding. Competitive salary (with benefits) will follow NIH guidelines commensurate with training and experience.


The applicants must have a PhD in Biology, Biophysics, Bioengineering, or equivalent with a general background in molecular/cellular biology and biophysics and essential wet lab skills. It is expected that the candidate has prior experience with mammalian cell cultures and some exposure to super resolution microscopy (e.g. PALM, STORM) and single-molecule tracking/TIRF for studying membrane proteins and associated biophysical processes. Familiarity with FRET and Fluorescence Complementation Assays would be advantageous, as well as experience with microscopy image analysis. Likewise, the candidate has to be collegiate and be able to communicate well with scientists from diverse backgrounds.

To apply:

Please send

(a) a cover letter including a brief statement explaining motivation and interest in the open position, summarizing past research and outlining career goals,

(b) a CV including a full list of publications and names and contact details of three references (with institutional mail/email addresses), and 

(c) one sample authored publication/manuscript 

by email to André Leier (aleier (at) uabmc.edu). Referees of short-listed candidates will be contacted directly. While the start date is negotiable, screening of applications will start immediately and will continue until the position is filled.

About us:

UAB is a highly collegial and interactive environment. UAB has an active Office of Postdoctoral Education (OPE) which provides mentoring and career guidance. UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable, and family-friendly environment. To learn more about the University of Alabama at Birmingham, please visit http://uab.edu/home.


Postdoc Awards and Benefits 

Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The OPE strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.

For further information, please contact Dr. André Leier (aleier (at) uabmc.edu) directly.

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